The metabolic role of GIP: physiology and pathology.
نویسنده
چکیده
منابع مشابه
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet.
The gut hormone gastric inhibitory polypeptide (GIP) plays a key role in glucose homeostasis and lipid metabolism. This study investigated the effects of administration of a stable and specific GIP receptor antagonist, (Pro(3))GIP, in mice previously fed a high-fat diet for 160 days to induce obesity and related diabetes. Daily intraperitoneal injection of (Pro(3))GIP over 50 days significantly...
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ورودعنوان ژورنال:
- Biochemical Society transactions
دوره 24 2 شماره
صفحات -
تاریخ انتشار 1996